off the top of the hat:
1) an individual matrix for all leds, or "led Group", could use alot of wire, may need code
2)individual driver for each LED(or 2), as example shown above, will need separate code too for each chip address
3) I am doing small project that will replace hard wired bus with "IR rx & IR repeaters" eliminating travel wires, but then each LED component needs its own source power, plus IR limits distance between, plus components maybe costly if you have alot of leds, plus needs code, plus i can't verify if it works, as this project is still in the making.