You need a "differential" amplifier. It can be a single precision opamp, or made from multiple opamps, or a ready made "instrumentation amplifer". These can be bought from Analog Devices, Linear Technology, Texas Instruments, National, Fairchild, and about fifty other makers. For starters, look up the data sheets and application notes for the INA12x (1<x<9) family of Instrumentation Amps.
Hi Mike, I have studied plenty on conditioning differential signals before I return and it really is time consuming . With so many manufacturers providing solutions . I need suggestions, the sensor spec says its driven by CC source (choosen) now if we need a swing of 0~5V at the IAs output what voltage should power the sensor.