I have made boards for many years, what I will discribe turns out very good quality and also allows making double sided boards that line up properly. One can use any number of pc drafting programs, there are shareware versions that work well for small to moderate boards, for example PADS PC ( a little old but fairly easy to learn ) but there are many others.
I use the photo method, I print my artwork onto transparencies designed for either laser or inkjet printers ( these are specially treated and must be printed on the proper side). I buy pre-sensitized "positive resist" pc board, lay the transparency on top, lay on a sheet of glass ,and exposure to UV light ( you can buy a single tube light for about $25). A standard 15W tube at a height of 1 1/2" will take about 1- 1 1/2 minutes ( do not stare at light source !, walk away for a while ). Once exposed, you develope with positive resist developer, the excess resist washes away and you are left with the pattern for etching. I use ammonium persulfate for etching, it works well and does not stain like ferric chloride ( as with any etchant it works best if warm, the ammonium persulfate I buy is in crystal form so I just mix it with hot water) after the etching is done rinse the board under cool water for a minute. The left over resist can be cleaned off with a solvent of a "Fine" Scotch-Brite pad.
Doing a double sided board is the same except lay both transparencies together, line them up, and remember that they must be opposed so one side doesn't become mirrored. Tape the two sheets together on 2 sides and slide your un-exposed board between an secure with a strip of tape so it doesn't move while handeling ( especially flipping it during exposure)
The process takes a little practice but can reveal excellent results. You can get all the basic materials for less than $100.00 which will make a number of boards. As a finishing touch you can buy "liquid Tin" to plate the finished boards for a real professional job. My best results come from using MG brand chemicals and GC brand presensitised boards ( no ad intended )
Use gloves, protect you eyes, and follow the safe handeling of the chemicals.