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i2c protocol

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I am using MPLab X with XC8 to write programs for a PIC18F46K22 & PIC18F45K22 to communicate via i2c with the PIC18F46K22 the master. When I send a write command from the master do I need to use the physical (Hex) memory address or will the compiler convert from the alias? Do I need to build the slave first and then define the address in a header for the master?
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afaik there is only the device address that is required ... the only thing i can think that would need to be pulled from memory(in host) is the device address or maybe the data you are sending
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