There are least a half dozen makers of micro controllers which are good choices.
Microchip, Atmel, Texas instruments, Cypress semi conductor, are a few that pop into my head. The question you asked is loaded, you're going to get a LOT of responses from people that are devoted to their particular favored line, and as blueroom said your application and specific needs are so important to the equation there's no way to answer the question properly without a LOT more information from you.