Triggering a mosfet with Proteus

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Try giving your voltage source that drives the gate a finite resistance (say 1Ω), or include a low value resistor in series with the gate.
boost 1.2V - 5V to 12Vout, 100W out
That may work in a sim, but is likely to cook a 1.2V battery in practice .
 
If you need to run from as low as 1.2V, then you need a mosfet that can switch with such low gate voltage, and there arent many and even less with high enough current, so bjt might be a better choice here.
 
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