wow, yes, it would, you have 230V running through your opamps!!!!
There shouldn't be much current in your sense amp loop, so I'd suggest putting a 10mA polyfuse before R2, that way, if your sense resistor opens, then the fuse will open before anything gets cooked.
But then, that's the problem, at 600V, they only have 150mA and 160mA hold currents, and at 250V, 80mA is the minimum... but I think 80mA will fry the opamp, especially on the input side. You could use a regular fuse (poly fuses are automatically resettable when the fault goes away). Of course, I just looked on digikey, they may have others...