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The latest MCU8051IDE comes un-built and trying to find TCL compiler is hard work... I have an earlier version at work that supports SDCC C compiler and the assembler... I'll try and dig it out... Its at work somewhere..
I've actually been using Keil uVision IDE, which comes with their A51 assembler and C51 compiler. Super simple to use IDE.
I use the Atmel AT89S8253 along with Atmel's AT89ISP programmer cable and AT89ISP software, but it requires a PC parallel port.
I'm sure it wouldn't be too difficult to design a programmer cable using an FTDI USB-SPI bridge chip such as the FT4222H. The AT89ISP software uses COM ports while the FTDI devices use FTDI's virtual COM port driver.
Now I haven't done it yet but I've toyed with the idea of making an UNO into a AT89S programmer. Atmel seems to have discontinued their AT89ISP cable and quite honestly, parallel port is so yesterday anyway.
I may also design a programmer cable with a FDTI FT221X USB-SPI bridge. Should be super simple to do. Since Atmel's software uses COM port drivers and FTDI has their virtual COM port driver it should work.
I've got my AT89S8253 samples, the little 88 cent development board, and I downloaded Keil, so with a bit more research I think I'll be ready for a programmer of some sort. I came across this chaps' Arduino AT89S52 Programmer and Windows app' and I might give it a try. If you get a chance, tell me what you think...