I don't use Multisim, but the idea is the same: capture schematic, assign values and run simulation. If you have more specific question you should be - specific.
As for amp, you need to describe what is your goal.
If you plan on sampling analog input like in your lik, there are two things you need:
- amplification of mic signal to match sampling circuit or ADC.
- filter to eliminate aliasing.
Mic output is usually low (mV) and ADC input range may be 0-5V for example (depends on your ADC and Vref). You would want to get the peak to peak of amplified signal to be large but within the limits of the ADC input range. Above circuit has three identical stages each with same gain. One can use single stage to get needed gain. If needed, gain can be adjustable (by replacing feedback resistor by trimmer pot for example).
OpAmp circuits are discussed everywhere, even Wiki has some info on it (and small example on deriving gain):
https://en.wikipedia.org/wiki/Opamp
note that opamps normally use dual supply. using them with single supply is done by creating virtual ground. circuit in your link does it too (10k/10k dividers).
gain of single stage is
Ainverting= - Rfbk/Rin = - R5/R2 = -R7/R6 = -R9/R8 = -10
three stages have combined gain of (-10)^3=-1000.
if it was non-inverting configuration, gain would be
Anoninv= 1 + (Rfbk/Rin)
As mentioned filtering is used to fix aliasing problem. Higher order filters have superior performance (sharper cutoff). One popular configuration is Sallen-Key.
Wiki shows an example (second order):
https://en.wikipedia.org/wiki/Sallen–Key_topology
Also you can get two opamps in DIP8 package.