You don't want any grounds near the trace antenna. Since two of the shield pads are near the antenna, I would say, leave ungrounded.
2.4 Module Mounting Details
Figure 2-1 and Figure 2-2 show the recommended
PCB footprint for the RN42 and RN42N, respectively.
When laying out the carrier board for the RN42 module,
the areas under the antenna and shielding connections
should not have surface traces, ground planes, or
exposed vias.