I started with the 18F family time ago and there is no comeback to the 16F.
Simplified banking scheme.
Specific registers to address reading from / writing to ports. Do not ignore their use!
An area in RAM where registers may be addressed anytime directly.
Indexing registers: you have more. Good to transfer blocks of data quite quickly.
W can be also treated like any SFR, taking advantage of the MOVFF instruction.
THere are the instructions to read / write tables. Very useful.
I use Assembler so I appreciate a lot the differences.
My suggestion: RTFM going straight to the instruction set. If you know the 16F you can have a good idea of the differences.
Buena suerte.